Welcome To SENOLAX

Click here to view senolax in pdf

 

By Dr.Kumar Pati

 

Dr. Abhay Kumar Pati is dedicated in promoting Biotechayur, a green company and it's subsidiaries/affiliates in Orissa, India to develop and market green technologies, products and services for improving healthcare, agriculture, nutrition and environment.

 

Dr. Abhay Kumar Pati was born in Raj-Nilgiri, Balasore District, Orissa, India. Dr. Pati was trained as a Physician in Calcutta at J.B. Ray State Ayurvedic Medical College & Hospital [Asthanga Ayurvedic College], which is one of the oldest Ayurvedic institutions in India, under Calcutta University. Dr. Pati came to U.S.A. almost 30 years (3 decades) ago on a fellowship. He was the publisher of an International Health Magazine called Health World. Dr. Pati is an author of several health books including, Vitamins and Herbal Digest, a 360 page book, which has been printed more than 7 times and sold over 800,000 copies in the world’s market. In this digest, readers can find nutritional, Ayurvedic, Chinese, Native American, South American herbal supplements and much, much more.

 

Senolax TM

 

A product formulated by Best Nutrition Inc, which contains Senna Leaves Extract 100mg with Bromelain Extract as an Enzyme 50mg

 

 

150 mg (500 capsules)

Price : $17.95

POSTAGE WILL BE CALCULATED
for DOMESTIC AND INTERNATIONAL

 

 

 

Senna

 

Senna (Cassia Angustifolia) is a shrub. It grows about two feets hights. It is found in India.

Senna is an Arabian name, and the drug was first brought into use by the Arabian physicians and later it was extensively used in Greek and Ayurvedic medicine of India.

 

Senna leaves have been traditionally used in Ayurvedic medicine as a natural herbal laxative.

 

Senna Leaves Extract 400mg with Bromelain, we have formulated as SENOLAX  Tablet. It is a  mild laxative

 

Therapeutics:

 

It is  a laxative herbal product, herbal laxative, natural laxative, constipation, mild cleansing herb.

 

Senna containing purgative that is used in only acute constipation Senna is a powerful cathartic in the treatment of  constipation working through a stimulation of intestinal peristalsis.

 

Senna leaves are used to treat  chronic constipation.

 

BROMELIANIN^TM :

 

A registered trademark of Best Nutrition Products Inc, USA.

 

Bromelain^TM can refer to one of two protease enzymes extracted from the plant family Bromeliaceae, or it can refer to a  combination of those enzymes along with other compounds produced in an extract.

 

500 mg (60 capsules)

Price : $9.95

POSTAGE WILL BE CALCULATED
for DOMESTIC AND INTERNATIONAL

 

 

COMPONENTS

Bromelain^TM is a mixture of sulfur-containing protein-digesting enzymes---called proteolytic enzymes or proteases—and several other substances in smaller quantities. 

The other substances include peroxidase, acid phosphatase, protease inhibitors, and calcium.

 

HISTORY

 

The first isolation of Bromelain^TM was recorded by the Venezuelan chemist Vicente Marcano in 1891 from the fruit of pineapple.  In 1892, Chittenden, assisted by Joslin and Meara, investigated the matter fully and called it ‘bromelin’.  Later the term ‘Bromelain^TM’ was introduced and originally applied to any protease from any plant member of the plant family Bromeliaceae.

 

Bromelain^TM was first introduced as a therapeutic supplement in 1957.  Research on apparently was first conducted in Hawaii but more recently has been conducted in countries in Asia, Europe and Latin America.  Germany has recently taken a great interest in Bromelain^TM research; Bromelain^TM is currently the 13th most widely used herbal medicine in Germany.

 

Bromelain^TM is present in all parts of the pineapple plant (Ananas comosus), but the stem is the most common commercial source, presumably because it is readily available after the fruit has been harvested.  Pineapples have had a long tradition as a medicinal plant among the natives of South and Central America.  However, just eating ppineapple will not give you a great deal of extra Bromelain^TM, because it is mostly concentrated in the stem, which is not nearly as tasty (albeit still edible).

 

USES

 

MEAT TENDERIZING

 

Along with papain, Bromelain^TM is one of the most Popular substances to use for meat tenderizing.

Historically, meat tenderizing enzymes were  often injected into the muscle of a food animal while it was still living.  This practice was deemed unethical, and has been largely discontinued, replaced with various postmortem application methods which are acceptable for lesser quality cuts.

 

Today, approximately 900% of meat tenderizer use is in consumer households.  Bromelain^TM is sold in a powdered form, which is combined with a marinade or directly sprinkled on the uncooked meat.  The enzyme will penetrate the meat and by a process called forking, cause the meat to be tender and palatable when cooked.  If the enzyme is allowed to work for too long, the meat may become too “mushy” for many consumers’ preferences

 

MEDICAL USES

 

Bromelain^TM can be used in a vast array of medical conditions.  It was first introduced in this area in 1957, and works by blocking some pro-inflammatory metabolites that accelerate and worsen the inflammatory process.  It is an anti-inflammatory agent, and so can be used for sports injury, trauma, arthritis, and other kinds of swelling.  It main uses are treatment of athletic injuries, digestive problems, phlebitis, sinusitis, and aiding healing after surgery.

 

It has also been proposed for the treatment of arthritis chronic venous insufficiency, easy bruising, gout, hemorrhoids, menstrual pain, autoimmune disorders, ulcerative colitis, and sinusitis.

 

Studies have shown that Bromelain^TM can also be useful in the reduction of platelet clumping and blood clots in the bloodstream, especially in the arteries.

 

It may have treatment potential for HIV.

 

A proprietary Bromelain^TMTM mixture, Debridase, has been developed by a Taiwanese biotechnology company, Challenge Bioproducts Co., Ltd., and an American doctor, Gerold Klein.  With the ability to distinguish dead tissues from living ones, Debridase has been used for third degree burn treatment.  An Israeli company, Mediwoound Ltd. Is now carrying out FDA phase II and III for the Debridase containing product, under the name of Debrase Gel Dressing.  Once the treatment is approved, it will be helping millions of patients world-wide.

 

Its side effects include nausea, vomiting, diarrhea, menorrhagia (excessively heavy menstrual flow) and possible allergic reactions.  One study has also associated Bromelain^TM with increased heart rate.

Bromelain^TM supplementation up to 460 mg has been shown to have no effect on human heart rate or blood pressure; however, increasing doses up to 1840 mg have been shown to increase the heart rate proportionately

 

PRODUCTION

 

It is produced in Thailand, Taiwan, and other tropical parts of the world where pineapples are grown.

Bromelain^TM is prepared from the stem part of the pineapple plant after harvesting the fruit.  This stem part is peeled, crushed and pressed to get the juice containing the soluble Bromelain^TM enzyme.

 

Further processing includes concentration of the pressed juice to get a purified enzyme.  This process is carried out in factories under strictly controlled conditions to assure microbiological quality and enzyme purity.

The Bromelain^TM products are all supplied as powder.

 

OTHER PLANT PROTEASES

 

Other plant proteases include papain (from the papaya), actinidin (from the kiwi fruit), and ficin (from the fig).  These proteases may induce a prickly sensation in the mouth when consumed.

 

Overview

 

Bromelain^TM is a mixture of protein-digesting enzymes found in pineapples (Ananas comosus). Bromelain^TM supplements contain active substances that aid digestion and help reduce inflammation.

 

Uses

 

Bromelain^TM is useful in the treatment of a wide range of conditions, but it is particularly effective in relieving inflammation associated with infection and physical injuries.

 

Studies have shown that Bromelain^TM may help in the treatment of the following:

 

Surgical Procedures and Sports Injuries

 

Although studies show mixed results, Bromelain^TM supplements may reduce swelling, bruising, healing time, and pain following surgery and physical injuries.  In fact, an authoritative body in Germany called the Commission E (similar to the U.S. Food and Drug Administration) approved the use of Bromelain^TM for these pruposes.

 

Wounds and Burns

 

Some studies of animals indicate that Bromelain^TM (applied to the surface of the skin) may be useful in removing dead tissue from third-degree burns (particularly burns that go through all layers of the skin).  This application has not yet been tested on people, but traditional and current day practices in Japan, Hawaii and Taiwan include use of topical Bromelain^TM to clean wounds and burns.  Similarly, some clinicians may recommend this topical agent to reduce swelling from insect bites or stings.

 

Nasal and Sinus Congestion

 

Although not all experts agree, Bromelain^TM supplements may help suppress cough, reduce nasal mucus associated with sinusitis, and relieve the swelling and inflammation caused by hay fever.  Bromelain^TM is approved by the German Commission E for the treatment of sinus and nasal swelling following ear, nose, and throat surgery or trauma.

 

Digestion

 

The protein-digesting enzymes found in Bromelain^TM help promote and maintain proper digestion and may relieve symptoms of stomach upset or heartburn, particularly when used in conjuction with other enzymes such as amylase (which digests starch) and lipase (which digest fats).  Similarly, an animal study suggests that the antibacterial effects of Bromelain^TM may help to control diarrhea caused by bacteria.  Studies in people are needed.

 

Arthritis and other Inflammatory Conditions

 

Bromelain^TM supplements may be as effective as some commonly used nonsteroidal anti-inflammatory (Nsaid) medications (such as ibuprofen and diclofenac) for reducing pain associated with osteoarthritis.  Similarly, preliminary studies suggest that Bromelain^TM may also help reduce the pain associated with rheumatoid arthritis.  Plus, long-standing use of Bromelain^TM suggests that this enzyme may be helpful as part of the treatment for other connective tissue disorders including scleroderma (build up of tough scar-like tissue in the skin and, at times, internal organs), bursitis, and tendonitis.

 

Infection

 

Some scientific evidence from test tubes and animals suggests that Bromelain^TM can fight against infectious agents such as viruses and bacteria.  Therefore, Bromelain^TM may prove a useful addition to conventional treatment of bronchitis, pneumonia, and urinary tract infections.  More research is needed

 

Amyloidosis

 

Amyloid is a protein-like substance that can build up and cause damage to many organs in the body such as the kidneys, liver, or heart.  This build-up of amyloid is called amyloidosis.  In one laboratory study, researchers examined the tissue of one person with a strong family history of amyloidosis.  They found that Bromelain^TM may help breakdown amyloid deposits in kidney tissue.  This very preliminary finding does not indicate how this information will translate to treatment or prevention of amyloidosis for people in general.  Much more research is needed.

 

Dietary Sources

 

Bromelain^TM is found in the common pineapple plant.

 

Available Forms

 

Bromelain^TM is available in tablet or capsule form for oral use.  It may also be used topically to treat severe burns.

 

How to Take It

 

Pediatric

 

There are no known scientific reports on the pediatric use of Bromelain^TM.  Therefore, use of this supplement is not currently recommended for children.

 

Adults

 

The German Commission E recommends 80 to 320 mg two to three times per day.  For specific conditions, higher doses may be prescribed as follows:

• Digestive aid: 500 mg per day in divided doses with meals
• Traumatic injuries: 500 mg four times a day on an empty stomach
• Joint inflammation: 500 to 2,000 mg a day in two divided doses 

Precautions

 

Because supplements may have side effects or interact with medications, they should be taken only under the supervision of a knowledgeable healthcare provider.  Bromelain^TM is generally recommended for no longer than 8 to 10 days in a row. 

 

Possible side effects from Bromelain^TM include nausea, vomiting, diarrhea, and excessive menstrual bleeding.

 

Individuals who are allergic to pineapples should not use Bromelain^TM supplements because skin reactions and/or asthma-like symptoms may occur.

 

Pregnant women and individuals with bleeding disorders, high blood pressure, and liver or kidney disease should consult a healthcare provider before taking Bromelain^TM.

Possible Interactions

 

If you are currently being treated with any of the following medications, you should not use Bromelain^TM without first talking to your healthcare provider.

 

Antibiotics

 

In a clinical study, the combination of Bromelain^TM and amoxicillin increased the levels of this antibiotic in the blood.  Some studies suggest that Bromelain^TM may increase the body’s ability to absorb tetracycline, but results of other studies have been conflicting.  Until studies confirm these results, it would be wise to avoid combining Bromelain^TM and tetracycline.

 

Studies with Bromelain^TM and tetracycline have produced mixed results.  Some research suggests that Bromelain^TM increases levels of the tetracycline in the body, while others indicate that it may cause more of the antibiotic  to be excreted in the urine.

 

Blood-thinning Medications

 

People taking aspirin, warfarin, or other medications that thin the blood should use Bromelain^TM with extreme caution because of a possible risk of bleeding when used together.

 

What is Bromelain^TM?

 

Bromelain^TM is a mixture of enzymes found naturally in the juice and stems of pinapples.  Called a proteolytic enzyme, Bromelain^TM is believed to help with the digestion of protein.

 

Some Bromelain^TM appears to be absorbed by the body intact, so it’s also thought to have effects outside the digestive tract.  In fact, Bromelain^TM is often marketed as a natural anti-inflammatory for conditions such as arthritis.  It’s one of the most popular supplements in Germany, where it is approved by the Commission E for the treatment of inflammation and swelling of the nose and sinuses due to surgery or injury.

 

Bromelain^TM is typically extracted from pineapples and made into capsule or tablet form.  Because it’s able to digest protein, Bromelain^TM is available in some grocery stores as a meat tenderizer.  A topical form of Bromelain^TM is also being explored experimentally for burns.

 

When used for as a digestive aid, Bromelain^TM is usually taken with meals.  When used for inflammatory conditions, practitioners typically recommend taking Bromelain^TM between meals on an empty stomach to maximize absorption.

 

Why Do People Use Bromelain^TM

*Surgery and Injuries

 

There is some evidence that Bromelain^TM supplements may reduce swelling, bruising, inflammation and pain after surgery and injury.  In Germany, Bromelain^TM has been approved for these uses by the Commission E since 1993.  Large, well-designed studies are needed, because not all studies have confirmed these results.

 

*Sinusitis

 

Bromelain^TM has been suggested as a complementary treatment for sinusitis.  Preliminary studies suggest that it may help reduce congestion, improve breathing and suppress coughing.  It’s approved by the Commission E as a complementary treatment for nasal and sinus swelling and inflammation after ear, nose and throat surgery. A review of three small but well-designed previously published studies found that Bromelain^TM may help relieve sinusitis symptoms.

 

Digestion

 

Bromelain^TM is a popular natural digestive aid due to it’s ability to digest proteins.  It’s used for bloating, gas and other digestive symptoms and for conditions such as irritable bowel syndrome.  Bromelain^TM is often used alone or in combination with other enzymes such as lipase, which digest fats, and amylase, which digests starch.  There is little research, however, on the safety or effectiveness of Bromelain^TM for digestion.

 

Osteoarthritis

 

Bromelain^TM may help with mild pain associated with osteoarthritis.  It’s common ingredient in nutritional supplements marketed as a natural pain remedy for arthritis.  Large, well-designed studies are needed to see if it is effective and to find out about possible side effects.

 

*Cancer

 

Bromelain^TM and other proteolytic enzymes have been explored as a complementary treatment for cancer.  Although there is some preliminary research, there isn’t enough evidence at this time on the safety or effectiveness of Bromelain^TM for cancer.  It should never be used in place of conventional treatment.
       

 Side Effects and Safety Concerns

 

Some of the more common side effects of Bromelain^TM include indigestion, nausea and diarrhea. Other side effects may include vomiting, increased heart rate, drowsiness and abnormal uterine bleeding or heavy menstruation .

 

Bromelain^TM has resulted in allergic reactions and asthma symptoms, including breathing problems, tightness in the throat, skin hives rash  or itchy skin. People with allergies to pineapples should avoid Bromelain^TM. Allergic reactions may also occur in people with allergies to latex, carrot, celery, fennel, rye, wheat, papain, bee venom or grass, birch or cypress pollens.

 

People with peptic ulcers should not use Bromelain^TM. People with other digestive disorders should consult a qualified healthcare professional before using Bromelain^TM.

 

Theoretically, Bromelain^TM may increase the risk of bleeding, so people with bleeding disorders and those taking medications that can increase the risk of bleeding should only use Bromelain^TM under the supervision of their physician. It should not be taken two weeks before or after dental procedures or surgery.

 

The safety of Bromelain^TM in pregnant or nursing women, children or people with liver or kidney disease isn’t  known.

 

Possible Drug and Herb Interactions 

 

  People taking “blood-thinners” (anticoagulant or anti-inflammatory), such as aspirin, warfarin (Coumadin), heparin, clopidogrel (plavix), non-steroidal anti-inflammatory medications such as ibuprofen (Motrin, Advil), naproxen (Naprosyn, Aleve) should only use Bromelain^TM under a physician’s supervision. It should also be used with caution by people taking herbs and supplements that are thought to increase the risk of bleeding, such as ginkgo biloba and garlic.

 

Studies suggest Bromelain^TM  may also increase the absorption of other medications, such as:

• amoxicillin, tetracycline and other antibiotics
• chemotherapy drugs such as 5-fluorouracil and vincristine
• ”ACE inhibitor” blood pressure medications such as captopril (Capoten) and lisinopril (Zestril)
• medications that cause drowsiness, such as benzodiazepines lorazepam (Ativan) or diazepam (Valium), some antidepressants, narcotics such as codeine, and barbiturates such as phenobarbitol.

Bromelain^TM Supplements

 

Bromelain^TM is an enzyme that is extracted from the stem and fruit of the pineapple. It is used to help reduce inflammation in the body, speed the  healing of wounds and bruises, and aid in the digestion of proteins. Preliminary studies suggest that it may also be beneficial in helping to fight cardiovascular disease and cancer.

 

Bromelain^TM is widely accepted as an effective treatment for pain and swelling caused by trauma (including sports injuries, surgery,and infections). Many studies have repeatedly demonstrated Bromelain^TM’s ability to help the body recover from injury more quickly by preventing the accumulation of fibrin and potent inflammatory substances, such as leukotrienes. The German Expert Panel (Commission E) has approved Bromelain^TM for treatment of swelling and athletic injuries, and recommends a dose of 80 to 120 milligrams two to three times daily.

 

There’s also strong evidence that taking 1,200 to 1,800 milligrams of Bromelain^TM each day can help relieve painful inflammation in those that suffer with rheumatoid arthritis. When combined with antibiotics, Bromelain^TM may also help reduce inflammation that accompanies sinusitis. Studies have shown that Bromelain^TM is beneficial for reducing swelling and improving breathing.

 

Bromelain^TM inhibits the aggregation (clumping) of platelets, and so it has been theorized that it might help prevent heart disease caused by plaque formation that could lead to a heart attack. It has been studied for its effectiveness in treating angina and Chronic Obstructive Pulmonary disease (COPD), both alone and in combination with other therapies. However, higher doses of Bromelain^TM may increase the heart rate and the effects of prescription blood thinner often prescribed to treat heart disease; people with cardiovascular disease should talk to their physician before trying bromelain supplements.

 

Bromelain may increase the absorption of some drugs, including antibiotics, chemotherapy drugs, and certain blood pressure medications. It has been theorized that bromelain may help cancer treatments be more successful. However, some researchers worry that bromelain could increase the effects of other medications as well,  most notably blood.

 

Bromelain^TMTM is a digestive enzyme like:

 

• Amylase
• Pancreatin
• Papin
• Pepsin